Development of novel analytical instrumentation and methodology based upon chemical separation science, hyphenated techniques, and multidimensional detection systems.

Selective, sensitive characterization and determination of thiolic compounds and proteins by fluorescence spectrometry and hyphenated techniques.

Development and application of a Dynamic Surface Tension Detector (DSTD) to the study of proteins and polymers at water/air interfaces and as detection system of surfactants for FIA and HPLC instrumentation.

Characterization of supramolecular Polyphenol-Chromium(III) Clusters by Molecular Dynamics Simulations Atomic spectrometry techniques (Atomic Absorption Spectrometry, Atomic Fluorescence Spectrometry); liquid chromatography (LC); hyphenated techniques (LC-AFS); development of analytical methods; protein analysis.

Flow Injection Analysis, surface tension measurements, polymer and protein surface activity, process analysis.

Molecular fluorescence and Trp phosphorescence spectroscopy, analysis of protein dynamic Spectroscopic techniques (Fourier Transform Infrared Spectroscopy, Circular Dichroism, UV/Visible spectroscopy, NMR spectroscopy), protein conformational analysis.

Electrochemistry (Differential Pulse Polarography and Voltammetry).

Development of analytical methods for the analysis of nitrosothiols and nitrosoproteins in biological fluids by chemical derivatization techniques and enzymatic reactions.

Conformational analysis of proteins by Fourier Transform Infrared Spectroscopy (FTIR).